Coffee drinkers might be less likely to develop the most common type of liver cancer[1] , hepatocellular carcinoma, according to a new review of studies.


Researchers from the Università degli Studi di Milan in Italy looked at 16 studies published between 1996 and 2012 that included data from 3,153 cases of hepatocellular carcinoma.


Coffee consumption was associated with a 40 percent decreased risk of hepatocellular carcinoma[2] , with some studies even suggesting a more than 50 percent decreased risk from drinking three cups of coffee a day.


However, it's still not known if coffee causes this decreased risk in liver cancer, or if people who have liver disease then try to drink less coffee, researchers noted.


"The inverse association might partly or largely exist because patients with liver and digestive diseases reduce their coffee intake. However, coffee has been shown to affect liver enzymes and development of cirrhosis, and therefore could protect against liver carcinogenesis," researchers wrote in the study.


The findings are published in the journal Clinical Gastroenterology and Hepatology[3] ; researchers noted this is the first meta-analysis on liver cancer and coffee published since 2007.


Coffee consumption has been linked in past research to decreased risks of a variety of other cancers, including prostate cancer[4] , oral cancer, basal cell carcinoma[5] (a type of skin cancer[6] ) and endometrial cancer[7] . However, moderation may be key -- a recent study also linked high coffee consumption with a higher risk of death for people[8] under age 55.



Need more reasons to keep up your cup of joe habit? Click through the slideshow:



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  • Coffee (Or At Least, The Caffeine!) Can Help You Proofread Better


    The caffeine in coffee could actually help you to <a href="http://psycnet.apa.org/psycinfo/2011-23154-001/" target="_hplink">spot grammar errors</a>, according to a new study in the <em>Journal of Experimental Psychology</em>. Researchers found that <a href="http://bodyodd.msnbc.msn.com/_news/2011/10/26/8498728-tank-up-on-java-unleash-your-inner-editor-says-study?ocid=twitter" target="_hplink">caffeine helped students to correct errors</a> in subject-verb agreement and verb tense, MSNBC reported. However, the caffeine still didn't seem to make a difference at identifying misspelled words -- sorry.




  • Coffee Could Lower Women's Depression Risk


    Women who drink a few cups of <a href="http://www.huffingtonpost.com/2011/09/27/coffee-cuts-depression-women_n_982122.html" target="_hplink">caffeinated coffee have a lower risk of depression</a> than women who don't drink any coffee, according to a Harvard study.

    That research, published in the <em>Archives of Internal Medicine</em>, shows that women who drink two to three cups of coffee a day have a 15 percent lower risk, while women who drink four or more cups of coffee a day have a 20 percent lower risk.

    Study research Dr. Albert Ascherio <a href="http://www.huffingtonpost.com/2011/09/27/coffee-cuts-depression-women_n_982122.html" target="_hplink">told HuffPost</a> earlier that "caffeine is known to affect the brain," because it "modulates the release of mood transmitters."

    "I'm not saying we're on the path to discovering a new way to prevent depression," he said. "But I think you can be reassured that if you are drinking coffee, it is coming out as a positive thing."




  • Coffee Could Save Your Brain


    ... Well, maybe. A study in the <em>Journal of Alzheimer's Disease</em> suggests that there's something in coffee -- though researchers have yet to determine what exactly that "something" is -- interacts with caffeine to boost the levels of granulocyte colony stimulating factor (GCSF), a growth factor that seems to be able to <a href="http://www.huffingtonpost.com/2011/06/24/coffee-could-ward-alzheimers_n_882931.html" target="_hplink">fight off Alzheimer's disease in mice</a>.

    The amount of coffee needed in the study is equivalent to about four or five cups of coffee for humans.

    Researchers said <a href="http://www.j-alz.com/press/2011/20110621.html" target="_hplink">GCSF likely has this effect</a> because it causes stem cells in the bone marrow to come into the brain and remove the beta-amyloid plaques associated with Alzheimer's disease. It also has a role in forming brain cell connections and creating new brain neurons, researchers said.




  • Coffee Could Lower Men's Prostate Cancer Risk


    A Harvard School of Public Health study shows that men who drink six cups of coffee a day have a 60 percent decreased <a href="http://www.huffingtonpost.com/2011/05/18/coffee-can-cut-prostate-c_n_863472.html" target="_hplink">chance of developing a dangerous form of prostate cancer</a>, as well as a 20 percent decreased chance of developing any other kinds of prostate cancer.

    The study, published in the <em>Journal of the National Cancer Institute</em>, also shows that just <a href="http://jnci.oxfordjournals.org/content/early/2011/05/17/jnci.djr151.abstract" target="_hplink">drinking just some coffee a day</a> -- just one to three cups -- could still cut prostate cancer risk by 30 percent.




  • Coffee Could Ward Off The World's Most Common Cancer


    New research presented at the American Association for Cancer Research conference shows that coffee could help to <a href="http://www.huffingtonpost.com/2011/10/24/coffee-most-common-cancer_n_1025089.html" target="_hplink">ward off basal cell carcinoma</a>, the most common cancer in the world.

    Researchers from Brigham and Women's Hospital and Harvard Medical School found that women who drink three or more cups of caffeinated coffee a day have a 20 percent lower risk of the skin cancer, while men had a 9 percent lower risk.

    Decaf coffee didn't seem to have the same protective effect -- so "our study shows that the inverse association with BCC appears due to caffeine, not other components in the coffee consumption," study researcher Fengju Song, Ph.D., earlier <a href="http://www.huffingtonpost.com/2011/10/24/coffee-most-common-cancer_n_1025089.html" target="_hplink">told HuffPost</a>.




  • Coffee Could Protect You From Type 2 Diabetes


    Drinking coffee is associated with a <a href="http://archinte.ama-assn.org/cgi/content/abstract/169/22/2053" target="_hplink">lower Type 2 diabetes risk</a>, with more coffee consumption linked to a greater decrease in risk, according to an <em>Archives of Internal Medicine</em> review of studies from 2009.

    In that review, researchers looked at data from more than 450,000 people in 18 studies, and found that for every extra cup of coffee drank a day, a person's risk of Type 2 diabetes decreased by 7 percent.

    However, researchers cautioned that "the putative <a href="http://archinte.ama-assn.org/cgi/content/abstract/169/22/2053" target="_hplink">protective effects of these beverages</a> warrant further investigation in randomized trials."




  • Coffee Could Decrease Parkinson's Risk


    Drinking <a href="http://www.ncbi.nlm.nih.gov/pubmed/20182023" target="_hplink">a few cups of coffee a day</a> could lower the risk of developing Parkinson's disease by as much as 25 percent, according to a study published last year in the <em>Journal of Alzheimer's Disease</em>.

    In that review of studies, which was published in the <em>Journal of Alzheimer's Disease</em>, researchers examined 26 studies that involved 125,000 British people, to find that <a href="http://www.telegraph.co.uk/health/healthnews/7815087/Coffee-can-cut-chances-of-developing-Parkinsons-disease-according-to-new-research.html" target="_hplink">two or three cups of coffee</a> seemed to have the optimal effect, <em>The Telegraph</em> reported.




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