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DOCTORS, GREAT TO HAVE YOU HERE.
THANK YOU SO MUCH.
>> THANK YOU.
>> FIRST, YOU BEGIN WITH SOME OF THE BIGGEST MEDICAL STOIES OF THE YEAR.
THE FIRST ONE IS REALLY A SHOCKING STUDY THIS YEAR, PREDICTING THE NUMBER OF PEOPLE LIVING WITH ALZHEIMER'S DISEASE IS EXPECTED TO TRIPLE.
TRIPLE, BY 2015.
DR.
SIEGEL, WHY SO MANY MORE? AND WHAT CAN WE ALL DO ABOUT IT? >> A LOT OF REASONS AND THIS IS A WELL-KNOWN SURVEY.
THEY LOOKED ADD 10,000 PATIENTS AT RUSH INSTITUTE AND FOLLOWED THEM FOR A DECADE.
THE REASON FOR THAT, NUMBER ONE ON THE LIST IS WE'RE GETTING OLDER.
MANY MORE BABY BOOMERS LIKE YOU AND ME, ERIC, AND WE'RE GETTING OLDER.
>> GENERATION X.
>> YEAH, OKAY.
SURE, SURE, ERIC, BUT THE MAIN THING IS THAT, YOU KNOW, MOST OF THESE ALZHEIMER'S PATIENTS ARE GOING TO BEOVER THE AGE OF 85.
THAT'S WHY THE BABY BOOMERS ARE GOING TO FILL THIS VOID.
THEN THE ISSUE OF OBESITY, PEOPLE NOT EXERCISING ENOUGH, NOT EATING RIGHT, BEING ON A LOT OF MEDICATIONS.
ALL OF THOSE CAN INCREASE YOUR RISK OF ALZHEIMER'S.
ASSOCIATED WITH THIS, WE'RE INCREASING YOUR ABILITY TO DISCOVER.
TWO STUDIES OUT IN DECEMBER HAVE LOOKED AT THIS.
A GROUNDBREAKING STUDY LOOKING AT PROTEINS WHICH WE HAVE DISCUSSED ON THE SHOW, AND IT'S VERY IMPORTANT IN FINDING ALZHEIMER'S BUT THEY FOR THE FIRST TIME LOOKED AT IT ON A MOLECULAR LEVEL AND FOUND EVEN INTRODUCING NORMAL PROTINES CAN CAUSE THE CELLS BE ABNORMAL.
THE OTHER PROTINE IS BETA AMALOID.
VERY IMPORTANT THAT PEOPLE WHO HAD BRAIN INJURIES, PEOPLE WHO HAD CONCUSSIONS, PEOPLE WHO HAD MEMORY LOSS WERE FIVE TIMES AS LIKELY TO FORM THOSE ABNORMAL BETA AMALOID PROTEINS, AND IMAGING STUDIES ARE IMPROVING OUR ABILITY TO FIND IT EARLY.
IF WE FIND IT EARLY AND FIND IT BEFORE IT'S ALREADY HIT YOU AND BEFORE IT COSTS BILLIONS OF DOLLARS TO OUR HEALTH CARE SYSTEM AND BEFORE CARETAKERS ARE OVERWHELMED, WE MIGHT BE ABLE TO FIND TREATMENTS TO USE.
>> YOU SAY TO YOUR DOCTOR, I WANT A TOW PROTEIN TEST? YOU KNOW YOUR LOVED ONES, IT'S THE MOST CRUCIAL, HORRENDOUS SITUATION TO GO THROUGH WHEN YOU SEE YOUR LOVED ONES.
>> IT NOT ONLY AFFECTS THE HEALTH CARE SYSTEM, BUT EMOTIONALLY, THE FAMILIES ARE INVOLVED.
WE'RE GOING TO SEE MORE AND MORE PEOPLE THAT WILL COME WITH ALZHEIMER'S.
THE GOVERNMENT SAYS THE NUMBERS WILL DOUBLE.
NOW WE'RE FINDING OUT IN THIS STUDY THAT IT'S GOING TO TRIPLE.
NOW, THIS IS EXPECTED BECAUSE AS PHYSICIANS OVER THE YEARS, WE TOOK CARE OF, YOU KNOW, QUANTITY.
WE TOOK CARE OF PROLONGING LIFE, HOW TO DEFEAT CANCER.
WE DID A GREAT JOB WITH HEART ATTACK.
THAT'S ONE OF THE REASONS PEOPLE ARE LIVING LONGER, BUT WE DON'T KNOW AND WE WERE NOT REALLY PREPARED FOR THE CAUSALITY OF LIFE.
THIS IS WHY ALZHEIMER'S WHICH BY THE WAY, IT'S NOT STANDING ALONE.
YOU'RE GOING TO HAVE BONE DISEASE, OSTEOPOROSIS, ISSUES THAT COME ALONG WITH THIS.
IN THE G-8 MEETING IN LONDON, THE PRIME MINISTER PUSHED FOR A WHOLE INITIATIVE WITH ALL WEALTHY COUNTRIES TO REALLY PUT AND INVEST MONEY IN RESEARCH.
WE TALKED ABOUT THE IMAGING.
THE GENETIC ASPECTS OF PHARMACEUTICALS TO TREAT ALZHEIMER'S BY 2025.
EVEN THOUGH IT'S A SHORT PERIOD TO CURE THIS DISEASE, PEOPLE NEED TO KNOW THAT ANYTHING THAT CAUSES ALZHEIMER'S.
IT'S SIMILAR TO HEART ATTACK.
OBESITY, SMOKING, DIABETES.
WE TALK ABOUT CONCUSSIONS.
THE FACT THAT IF YOU'RE NOT ACTIVE, IF YOU DON'T EXERCISE, ALL OF THOSE ARE RISK FACTORS.
YOU WANT TO ENGAGE YOUR BRAIN IN SOLVING PUZZLES, LEARNING A NEW LANGUAGE.
AS LONG AS YOU'RE ACTIVE, YOU CAN DELAY IT.
I THINK THERE'S HOPE.
>> HEREDITARY COMPONENT? >> A PART OF IT, BUT ALSO THOSE FAMILIES, WE WANT TO MAKE SURE WE DIAGNOSE THEM EARLY.
WE'RE GOING FROM 5 MILLION NUMBERS IN AMERICA TO ABOUT 14 MILLION.
AND ABOUT 7 MILLION OF THEM ARE BABY BOOMERS WHO ARE GOING TO LIVE OVER 85.
SO THIS IS GOOD NEWS, BUT WE'RE GOING TO HAVE A LOT OF SICKER POPULATION IN OUR HANDS THAT WE HAVE TO DEAL WITH.
>> WHAT DO I TELL MY DOCTOR? WHAT DO I LOOK FOR? >> THE FIRST THING YOUR DOCTOR IS GOING TO SAY IS FIVE YEARS FROM NOW, WE'RE GOING TO HAVE IMAGING STUDIES AND TELL YOU IF YOU'RE AT RISK AND WHAT YOUR PERCENTAGE IS.
>> FIVE YEARS FROM NOW.
>> IF YOU NEED TO EXERCISE MORE AND YOUR DIET, AND MAYBE THERE WILL BE DRUGS OUT THERE THAT WILL TARGET THE PROTEINS OR BETA AMYLOID PROTEINS BEFORE THEY FORM.
THERE ARE CERTAIN PEOPLE WHO WILL GET AND OTHERS WON'T.
GROUPS OF PEOPLE WILL GET TREATMENT, OTHERS WON'T NEED IT.
>> YOU CAN GO TO A DOCTOR, THESE ARE PART OF RESEARCH.
THIS IS AT THE VERY MOLECULAR LEVEL, BUT IN THE FUTURE, WE'LL BE ABLE TO DIAGNOSE IT EARLY ON.
>> WHAT YOU'RE SAYING IS MORE OF US WILL HAVE IT WHILE WE'RE TAKING CARE OF PARENTS WHO HAVE IT IF THERE'S A GENETIC LINK.
>> MEANWHILE, THERE WAS ANOTHER POTENTIAL NEW WEAPON IN THE BATTLE OF THE BULGE AS WE COVER SOME OF YOUR BIGGEST MEDICAL
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